Palmitoyl Tetrapeptide-7

Pal-GQPR Rigin™

Palmitoyl Tetrapeptide-7 (also known as Rigin™; former INCI name: Palmitoyl Tetrapeptide-3) is a lipopeptide from Sederma designed to mimic DHEA activity and restore cytokine balance to mature skin. The lipo-tetrapeptide with sequence Pal-GQPR, a fragment of immunoglobulin G, is sometimes referred to as the "youth hormone molecule."

DHEA (Dehydroepiandrosterone) decreases with aging, causing an increase in interleukin-6. Palmitoyl Tetrapeptide-7 helps skin look younger by correcting this imbalance and reducing the basal and UV-induced secretions of interleukin-6 in the keratinocytes and fibroblasts, just as DHEA does.

Products containing Palmitoyl Tetrapeptide-7

Environ Antioxidant & Peptide Eye Gel
e
15 ml / 2.1 fl oz
C
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Environ Vita-Peptide Toner
e
200 ml
C
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Environ Vita-Antioxidant AVST Moisturiser 3
e
50 ml / 1.7 fl oz
C
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Environ Vita-Peptide Eye Gel
e
10ml/0.35 fl oz
C
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Environ Vita-Peptide C-Quence Serum 1
e
35 ml / 1.18 fl oz
C
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Environ Vita-Peptide C-Quence Serum 2
e
35 ml / 1.18 fl oz
C
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F.A.Q.: 

How Palmitoyl Tetrapeptide-7 keeps the skin younger?

Palmitoyl Tetrapeptide-7 reduces Interleukin-6 (IL-6) production by the critical cells keratinocytes and fibroblasts in the skin. Interleukin-6 is a mediator of inflammation that leads to more rapid degradation of the extracellular matrix components, promoting wrinkles formation and lessening firmness and elasticity of the skin.

Reduction of IL-6 and other pro-inflammatory agents, Palmitoyl Tetrapeptide-7, protects extracellular matrix components from degradation, preserving skin's natural youthfulness and boosting its replenishment.